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  • Environments

    The AWS CDK CLI follows a protocol similar to the AWS CLI to determine which AWS credentials to use when performing operations against your AWS account. See AWS CDK Toolkit (cdk command) for details. For production stacks, we recommend that you explicitly specify the environment for each stack in your app using the env property.

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    Option 1: pass the data from Stack A to Stack B using the constructor : You can extend cdk.stack and create a new class that will contain stackA.. In that stack, expose the relevant data you want by using public XXX: stringnumber (etc) ( See line 2 in the example).. Later, just pass this data into StackB constructor ( you can pass it using props as well).

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    SU 9516 is a 3-substituted indolinone CDK inhibitor with IC50 of 22 nM, 40 nM, and 200 nM for CDK2, CDK1, and CDK4, respectively. Ro-3306 New. RO-3306 is an ATP-competitive, and selective CDK1 inhibitor with K i of 20 nM, >15-fold selectivity against a diverse panel of human kinases. RO-3306 enhances p53-mediated Bax activation and ...

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    SU9516 New SU 9516 is a 3-substituted indolinone CDK inhibitor with IC50 of 22 nM, 40 nM, and 200 nM for CDK2, CDK1, and CDK4, respectively.. Ro-3306 New RO-3306 is an ATP-competitive, and selective CDK1 inhibitor with K i of 20 nM, >15-fold selectivity against a diverse panel of human kinases. RO-3306 enhances p53-mediated Bax activation and mitochondrial apoptosis.

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     · In the 2000s, the role of CDK/cyclin complexes in transcription and mRNA processing was first reported. 23 Although the CDKs involved in transcription have overlapping substrate specificities around CTD-RNAPII, they play largely non-redundant roles in gene expression modulation. Within the transcriptional CDKs sub-branch, CDK7, 8/19 and 9 are found as components of general transcription …

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